Description

5-Methyl-2-(Trifluoromethyl)-Dl-Phenylalanine is a non-natural, fluorinated amino acid derivative of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring a trifluoromethyl group and a methyl substituent on the phenyl ring, imparts valuable properties such as enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, peptide mimetics, and as a sophisticated building block for novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly protease inhibitors and enzyme modulators.
• Peptidomimetics Research: Used to incorporate fluorinated motifs into peptide backbones to enhance stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Employed in the development of advanced pesticides and herbicides where the trifluoromethyl group can improve activity and environmental profile.
• Chemical Biology Probes: Utilized in the design of labeled compounds and probes for studying biological mechanisms and protein interactions.
• Material Science Precursor: Acts as a specialty monomer or precursor for advanced polymers and coatings with specific fluorinated characteristics.

Basic Information

Product Name	5-Methyl-2-(Trifluoromethyl)-Dl-Phenylalanine
CAS No.	1256482-64-0
Molecular Formula	C11H10F3NO2
Molecular Weight	245.20 g/mol
Synonyms	DL-5-Methyl-2-(trifluoromethyl)phenylalanine; 2-Amino-3-[5-methyl-2-(trifluoromethyl)phenyl]propanoic acid; (RS)-2-Amino-3-(5-methyl-2-(trifluoromethyl)phenyl)propanoic acid; 5-Methyl-2-trifluoromethyl-DL-phenylalanine; α-Amino-5-methyl-2-(trifluoromethyl)benzenepropanoic acid; NSC 865209; Benzenepropanoic acid, α-amino-5-methyl-2-(trifluoromethyl)-, (±)-
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-(Trifluoromethyl)-Dl-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.