Description

Lithium Triisopropyl 2-(6-Fluoropyridyl)Borate is a specialized organoboron reagent featuring a fluoropyridyl ligand, which imparts unique reactivity and stability. This compound is a high-value intermediate critical for advanced cross-coupling reactions in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing complex molecular architectures.

Application

• As a key boron-based coupling partner in Suzuki-Miyaura cross-coupling reactions for C-C bond formation.
• Intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated heterocycles.
• Precursor for the development of novel organic electronic materials and ligands for catalysis.
• Used in agrochemical research for creating new molecules with potential herbicidal or insecticidal activity.
• Building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Reagent in methodological development for new boron-mediated transformation processes.

Basic Information

Product Name	Lithium Triisopropyl 2-(6-Fluoropyridyl)Borate
CAS No.	1256364-28-9
Molecular Formula	C14H23BF1LiN1
Molecular Weight	243.10 g/mol (Contact for exact details)
Synonyms	Lithium (6-Fluoropyridin-2-yl)triisopropylborate; Triisopropyl(6-fluoro-2-pyridinyl)boron Lithium Salt; 2-(6-Fluoropyridyl)triisopropylborolithium; (6-Fluoro-2-pyridinyl)triisopropylborate Lithium Complex; Lithium Triisopropyl(6-fluoro-2-pyridinyl)borate; B-Li Reagent with 6-Fluoropyridyl Group
EINECS	Contact for details

Quality Control

Our production of Lithium Triisopropyl 2-(6-Fluoropyridyl)Borate adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized by NMR (1H, 11B, 19F) and HPLC analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (argon or nitrogen) due to its moisture-sensitive and potentially air-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.