Description

2H-1-Benzopyran-7-Ol, 8-Chloro-3,4-Dihydro- is a high-purity, synthetically derived chroman derivative, a key structural motif in medicinal chemistry. This compound serves as a crucial advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic frameworks and fused ring systems.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic and receptor-binding studies due to its chroman core.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and high-value agrochemical intermediates.

Basic Information

Product Name	2H-1-Benzopyran-7-Ol, 8-Chloro-3,4-Dihydro-
CAS No.	1256255-23-8
Molecular Formula	C9H9ClO2
Molecular Weight	184.62 g/mol
Synonyms	8-Chloro-3,4-dihydro-2H-1-benzopyran-7-ol; 8-Chloro-7-hydroxy-3,4-dihydro-2H-chromene; 8-Chloro-7-hydroxy-3,4-dihydro-2H-1-benzopyran; 8-Chloro-7-hydroxy-2,3-dihydrochromene; 8-Chloro-7-hydroxy-2,3-dihydro-1-benzopyran; 8-Chloro-7-hydroxy-3,4-dihydro-2H-chromen-7-ol; 1256255-23-8
EINECS	Contact for details

Quality Control

Our production of 2H-1-Benzopyran-7-Ol, 8-Chloro-3,4-Dihydro- adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles for every lot. Our quality systems are designed to support cGMP compliance for advanced intermediates, ensuring suitability for demanding pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.