Description

(3,4-Dihydro-2H-Chromen-6-Ylmethyl)Amine Hydrochloride is a high-purity chromane derivative building block essential for advanced pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of novel active molecules, offering a versatile scaffold for medicinal chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and crop protection industries seeking to develop new therapeutic and agrochemical agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and inflammatory conditions.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its chromane core, a privileged structure in drug discovery.
• Agrochemical Synthesis: Intermediate in the development of new generation pesticides and herbicides, leveraging its heterocyclic framework.
• Chemical Biology Probes: Serves as a precursor for designing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.
• Academic Research: Used in university and institutional labs for fundamental organic synthesis and methodology development.

Basic Information

Product Name	(3,4-Dihydro-2H-Chromen-6-Ylmethyl)Amine Hydrochloride
CAS No.	1255718-26-3
Molecular Formula	C11H14ClNO
Molecular Weight	211.69 g/mol
Synonyms	6-(Aminomethyl)-3,4-dihydro-2H-1-benzopyran hydrochloride; 2H-1-Benzopyran-6-methanamine, 3,4-dihydro-, hydrochloride; Chroman-6-ylmethylamine hydrochloride; 6-(Aminomethyl)chroman hydrochloride; (Chromane-6-yl)methanamine hydrochloride; 3,4-Dihydro-2H-chromene-6-methanamine hydrochloride; 6-Aminomethyl-3,4-dihydro-2H-chromene hydrochloride
EINECS	Contact for details

Quality Control

Our (3,4-Dihydro-2H-Chromen-6-Ylmethyl)Amine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom synthesis to specific purity grades (e.g., >98%, >99%) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.