Description

4-(2-Fluoroethyl)Tetrahydro-2H-Pyran-4-Carbonitrile is a versatile fluorinated heterocyclic building block, specifically a nitrile-substituted tetrahydropyran derivative. Its molecular structure, featuring both a fluorine atom and a nitrile group, makes it a valuable intermediate for synthesizing more complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for use in medicinal chemistry and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the fluorinated pyran structure can enhance biological activity.
• Material Science Research: Serves as a precursor for developing specialty polymers and liquid crystals with unique electronic or optical properties.
• Chemical Biology Probes: Utilized in the synthesis of fluorinated probes and tags for studying biological mechanisms and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	4-(2-Fluoroethyl)Tetrahydro-2H-Pyran-4-Carbonitrile
CAS No.	1255147-18-2
Molecular Formula	C8H12FNO
Molecular Weight	157.18 g/mol
Synonyms	4-(2-Fluoroethyl)oxane-4-carbonitrile; 4-(2-Fluoroethyl)tetrahydropyran-4-carbonitrile; 4-Cyano-4-(2-fluoroethyl)tetrahydropyran; Tetrahydro-2H-pyran-4-carbonitrile, 4-(2-fluoroethyl)-; 1255147-18-2
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Fluoroethyl)Tetrahydro-2H-Pyran-4-Carbonitrile is produced under strict quality management protocols. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.