Description

2-[2-Chloro-4-(Trifluoromethyl)Phenyl]-5,7-Dihydroxy-8-[(2R,3S)-2-(Hydroxymethyl)-1-Methylpyrrolidin-3-Yl]Chromen-4-One is a high-purity, complex heterocyclic compound featuring a chromen-4-one (flavone) core with a substituted phenyl ring and a chiral pyrrolidine moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate or reference standard for research and development. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams working on novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity.
• Biochemical Tool Compound: Potential use in in-vitro assays to study biological mechanisms and interactions.
• Fine Chemical Synthesis: Intermediate for the production of more complex, high-value specialty chemicals.

Basic Information

Product Name	2-[2-Chloro-4-(Trifluoromethyl)Phenyl]-5,7-Dihydroxy-8-[(2R,3S)-2-(Hydroxymethyl)-1-Methylpyrrolidin-3-Yl]Chromen-4-One
CAS No.	1253731-24-6
Molecular Formula	C23H21ClF3NO6
Molecular Weight	499.87 g/mol
Synonyms	8-[(2R,3S)-2-(Hydroxymethyl)-1-methylpyrrolidin-3-yl]-5,7-dihydroxy-2-[2-chloro-4-(trifluoromethyl)phenyl]chromen-4-one; (2R,3S)-8-[2-(Hydroxymethyl)-1-methyl-3-pyrrolidinyl]-5,7-dihydroxy-2-[2-chloro-4-(trifluoromethyl)phenyl]-4H-1-benzopyran-4-one; Flavone derivative with chlorotrifluoromethylphenyl and hydroxymethylpyrrolidine substituents; Complex Flavone Intermediate; CAS 1253731-24-6
EINECS	Contact for details

Quality Control

Our 2-[2-Chloro-4-(Trifluoromethyl)Phenyl]-5,7-Dihydroxy-8-[(2R,3S)-2-(Hydroxymethyl)-1-Methylpyrrolidin-3-Yl]Chromen-4-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); therefore, containers must be kept tightly sealed and desiccated to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.