Description

8-Nitro-4-Oxo-4H-Chromene-3-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. This compound is valued for its unique chromene scaffold functionalized with both nitro and aldehyde groups, enabling its use in complex organic synthesis and medicinal chemistry research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and CNS disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Building block for developing new active ingredients in crop protection and pesticide formulations.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing specialized chromene-based dyes and functional colorants.
• Material Science Research: Utilized in the development of organic electronic materials and photoactive compounds.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in heterocyclic and nitro chemistry.

Basic Information

Product Name	8-Nitro-4-Oxo-4H-Chromene-3-Carbaldehyde
CAS No.	1253654-82-8
Molecular Formula	C10H5NO5
Molecular Weight	219.15 g/mol
Synonyms	8-Nitro-4-oxo-4H-chromene-3-carboxaldehyde; 3-Formyl-8-nitro-4H-chromen-4-one; 8-Nitro-4-oxo-4H-1-benzopyran-3-carbaldehyde; 4-Oxo-8-nitro-4H-chromene-3-carbaldehyde; 8-Nitro-4-oxochromene-3-carbaldehyde; 3-Aldehyde-8-nitro-4-chromone
EINECS	Contact for details

Quality Control

Our 8-Nitro-4-Oxo-4H-Chromene-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.