Description

3-Bromo-4-(2,6-Difluorophenyl)Butan-2-One is a high-value, fluorinated organic building block with the CAS number 1251040-66-0. This compound is a critical intermediate in modern synthetic chemistry, prized for its unique halogenated and fluorinated aromatic structure that enables the construction of complex molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of new active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the difluorophenyl moiety can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its halogenated structure to modify material properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitutions to introduce complex fluorinated side chains.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical production.

Basic Information

Product Name	3-Bromo-4-(2,6-Difluorophenyl)Butan-2-One
CAS No.	1251040-66-0
Molecular Formula	C10H9BrF2O
Molecular Weight	263.08 g/mol
Synonyms	3-Bromo-4-(2,6-difluorophenyl)butan-2-one; 1-(2,6-Difluorophenyl)-3-bromobutan-2-one; 3-Bromo-1-(2,6-difluorophenyl)butan-2-one; 2-Butanone, 3-bromo-4-(2,6-difluorophenyl)-; 1251040-66-0; 3-Bromo-4-(2,6-difluorophenyl)-2-butanone
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(2,6-Difluorophenyl)Butan-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under ISO and cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.