Description

3A-(4-Bromo-Phenyl)-Hexahydro-Pyrano[3,4-B]Pyrrole-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for constructing novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged pyrrolidine-pyran scaffold.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredient (API) production under cGMP conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	3A-(4-Bromo-Phenyl)-Hexahydro-Pyrano[3,4-B]Pyrrole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1251015-93-6
Molecular Formula	C18H22BrNO3
Molecular Weight	380.28 g/mol
Synonyms	tert-Butyl 3a-(4-bromophenyl)hexahydropyrano[3,4-b]pyrrole-1-carboxylate; 1-(1,1-Dimethylethyl) 3a-(4-bromophenyl)hexahydro-2H-pyrano[3,4-b]pyrrole-1,5-dicarboxylate (related ester); 3a-(4-Bromophenyl)octahydropyrano[3,4-b]pyrrole-1-carboxylic acid tert-butyl ester; 1251015-93-6; 4-Bromo-phenyl substituted pyranopyrrolidine tert-butyl ester; Bromophenyl hexahydropyranopyrrole carboxylate
EINECS	Contact for details

Quality Control

Every batch of 3A-(4-Bromo-Phenyl)-Hexahydro-Pyrano[3,4-B]Pyrrole-1-Carboxylic Acid tert-Butyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) including HPLC purity, NMR, and mass spec confirmation is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.