Description

4-(2-Chloro-Phenyl)-Tetrahydro-Pyran-4-Carbonitrile is a versatile and high-value pharmaceutical intermediate. This compound is crucial for the synthesis of complex molecules, offering a unique structural motif that enables key chemical transformations. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients. The compound, CAS NO 1250512-48-1, is supplied under stringent quality control to ensure batch-to-batch consistency for critical R&D and production processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its chlorophenyl and nitrile functional groups.
• Chemical Synthesis: Serves as a precursor for creating more complex heterocyclic compounds and fine chemicals in laboratory and pilot-scale operations.
• Material Science: Potential monomer or additive in the research of specialty polymers with specific optical or electronic properties.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic and contract research organizations (CROs).

Basic Information

Item	Detail
Product Name	4-(2-Chloro-Phenyl)-Tetrahydro-Pyran-4-Carbonitrile
CAS No.	1250512-48-1
Molecular Formula	C12H12ClNO
Molecular Weight	221.68 g/mol
Synonyms	4-(2-Chlorophenyl)tetrahydro-2H-pyran-4-carbonitrile; 2H-Pyran-4-carbonitrile, tetrahydro-4-(2-chlorophenyl)-; 4-(2-Chlorophenyl)oxane-4-carbonitrile; 4-(2-Chloro-phenyl)-tetrahydropyran-4-carbonitrile; 4-(o-Chlorophenyl)tetrahydropyran-4-carbonitrile; Tetrahydro-4-(2-chlorophenyl)-2H-pyran-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-(2-Chloro-Phenyl)-Tetrahydro-Pyran-4-Carbonitrile is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.