Description

3-[3-(Aminomethyl)Phenyl]-1,3-Oxazinan-2-One is a specialized organic compound featuring a unique oxazinanone scaffold linked to an aminomethylphenyl group. This structure makes it a valuable pharmacophore and key building block in modern synthetic chemistry, particularly for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Protease Inhibitor Research: Serves as a core scaffold for developing inhibitors of specific enzymes like proteases, which are relevant in various disease pathways.
• Chemical Biology & Medicinal Chemistry: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for clinical trials.
• Academic Research: Employed in university and institutional labs for methodological development and exploring new chemical reactions involving constrained heterocycles.

Basic Information

Product Name	3-[3-(Aminomethyl)Phenyl]-1,3-Oxazinan-2-One
CAS No.	1250502-21-6
Molecular Formula	C12H16N2O2
Molecular Weight	220.27 g/mol
Synonyms	3-(3-(Aminomethyl)phenyl)-1,3-oxazinan-2-one; 3-(3-(Aminomethyl)phenyl)-2-oxo-1,3-oxazinan-2-one; 1,3-Oxazinan-2-one, 3-[3-(aminomethyl)phenyl]-; 3-(3-Aminobenzyl)-1,3-oxazinan-2-one; 3-(3-(Aminomethyl)phenyl)oxazinan-2-one; (3-(2-Oxo-1,3-oxazinan-3-yl)phenyl)methanamine; 1250502-21-6 (CAS Name)
EINECS	Contact for details

Quality Control

Our production of 3-[3-(Aminomethyl)Phenyl]-1,3-Oxazinan-2-One adheres to stringent quality protocols suitable for pharmaceutical research. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP (where applicable) requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.