Description

4-[(Tetrahydropyran-4-Yl)Amino]-1-Butanol is a versatile amino alcohol derivative featuring a tetrahydropyran ring, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its bifunctional nature, containing both a hydroxyl and a secondary amino group, makes it a critical precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and catalyst design.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Ligand and Catalyst Precursor: Used in the synthesis of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Intermediate for creating novel fungicides and herbicides with specific stereochemical requirements.
• Polymer Modification: Acts as a chain extender or cross-linking agent in the synthesis of specialty polyurethanes and epoxy resins.
• Chemical Biology Probe Development: Building block for synthesizing molecular probes and linkers used in bioconjugation and target identification.
• Academic & Industrial R&D: Fundamental research reagent for exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	4-[(Tetrahydropyran-4-Yl)Amino]-1-Butanol
CAS No.	1249168-55-5
Molecular Formula	C9H19NO2
Molecular Weight	173.25 g/mol
Synonyms	4-[(Tetrahydropyran-4-yl)amino]butan-1-ol; 1-Butanol, 4-[(tetrahydro-2H-pyran-4-yl)amino]-; 4-(Tetrahydropyran-4-ylamino)butan-1-ol; 4-(Oxan-4-ylamino)butan-1-ol; THP-Amino-Butanol; 4-Amino-1-butanol, N-(tetrahydro-2H-pyran-4-yl)-; 1249168-55-5
EINECS	Contact for details

Quality Control

Our 4-[(Tetrahydropyran-4-Yl)Amino]-1-Butanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP compliance for advanced intermediates and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.