Description

4H-Azepin-4-One, 3-Bromohexahydro-5-Methyl-1-[(4-Methylphenyl)Sulfonyl]- is a specialized heterocyclic sulfonamide building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic cores.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its sulfonamide and brominated azepinone structure.
• Chemical Biology Probe Synthesis: Employed as a scaffold for creating tool compounds and probes to study biological pathways and protein function.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers and specialty materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic Research: Utilized in university and institutional laboratories for methodological development in organic chemistry and medicinal chemistry projects.

Basic Information

Product Name	4H-Azepin-4-One, 3-Bromohexahydro-5-Methyl-1-[(4-Methylphenyl)Sulfonyl]-
CAS No.	1247885-24-0
Molecular Formula	C14H18BrNO3S
Molecular Weight	360.27 g/mol
Synonyms	3-Bromo-5-methyl-1-(4-methylphenyl)sulfonyl-hexahydro-4H-azepin-4-one; 1-(4-Methylbenzenesulfonyl)-3-bromo-5-methylhexahydro-4H-azepin-4-one; 3-Bromo-5-methyl-1-tosylhexahydro-4H-azepin-4-one; 3-Bromo-5-methyl-1-(p-tolylsulfonyl)azepan-4-one; Hexahydro-3-bromo-5-methyl-1-[(4-methylphenyl)sulfonyl]-4H-azepin-4-one; Brominated Azepinone Sulfonamide; Tosyl Azepinone Bromide Derivative
EINECS	Contact for details

Quality Control

Our 4H-Azepin-4-One, 3-Bromohexahydro-5-Methyl-1-[(4-Methylphenyl)Sulfonyl]- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.