Description

4-Bromo-α-(Fluoromethyl)Benzenemethanamine is a specialized aromatic amine derivative featuring both bromo and fluoromethyl substituents, making it a valuable bifunctional building block in advanced organic synthesis. This compound is critical for medicinal chemistry research, enabling the rapid construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs) and agrochemical intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and fungicides, leveraging the halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent or affinity tags for studying biological targets and pathways.
• Custom Synthesis Building Block: Provides a versatile handle for parallel and combinatorial library synthesis in contract research organizations (CROs).

Basic Information

Product Name	4-Bromo-α-(Fluoromethyl)Benzenemethanamine
CAS No.	1246567-29-2
Molecular Formula	C8H9BrFN
Molecular Weight	218.07 g/mol
Synonyms	4-Bromo-α-(fluoromethyl)benzylamine; (4-Bromophenyl)(fluoromethyl)methanamine; 1-(4-Bromophenyl)-2-fluoroethanamine; Benzenemethanamine, 4-bromo-α-(fluoromethyl)-; α-(Fluoromethyl)-4-bromobenzylamine; 4-Bromo-α-fluoromethylbenzylamine; (4-Bromobenzyl)(fluoromethyl)amine
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-α-(Fluoromethyl)Benzenemethanamine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.