Description

Potassium Trifluoro(6-(Trifluoromethyl)Pyridin-3-Yl)Borate is a specialized organoboron reagent featuring a pyridine ring substituted with trifluoromethyl and trifluoroborate groups. This compound is valued for its role as a key synthetic intermediate, particularly in cross-coupling reactions, enabling the efficient construction of complex fluorinated molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and production of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant organoboron reagent for the introduction of the (6-(trifluoromethyl)pyridin-3-yl) moiety into target molecules.
• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated heterocycles for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorinated pyridine unit contributes to efficacy and environmental profile.
• Material Science Research: Employed in the creation of novel fluorinated organic materials, such as ligands for catalysis or components for electronic materials.
• Medicinal Chemistry & Drug Discovery: Enables rapid parallel synthesis and library generation for structure-activity relationship (SAR) studies in early-stage research.

Basic Information

Product Name	Potassium Trifluoro(6-(Trifluoromethyl)Pyridin-3-Yl)Borate
CAS No.	1245906-75-5
Molecular Formula	C6H3BF6KN
Molecular Weight	244.00 g/mol
Synonyms	Potassium (6-(Trifluoromethyl)pyridin-3-yl)trifluoroborate; 3-Pyridineboronic acid, 6-(trifluoromethyl)-, potassium trifluoroborate salt; (6-(Trifluoromethyl)-3-pyridinyl)trifluoroborate potassium salt; Potassium (6-(Trifluoromethyl)-3-pyridyl)trifluoroborate; 6-(Trifluoromethyl)pyridine-3-boronic acid potassium trifluoroborate salt; 3-Boronic acid, 6-(trifluoromethyl)pyridine, potassium trifluoroborate complex
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro(6-(Trifluoromethyl)Pyridin-3-Yl)Borate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
NMR Purity (19F)	≥ 95%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.