Description

Potassium Trifluoro(5-Methyl-1,3,4-Thiadiazol-2-Yl)Borate is a specialized organoboron salt, serving as a key reagent in advanced synthetic chemistry. Its primary value lies in its role as a stable and effective source of the trifluoroborate anion, which is crucial for facilitating challenging cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and complex molecular scaffolds. Its utility extends to materials science for the development of functional organic materials.

Application

• Pharmaceutical Intermediate Synthesis: A critical building block for constructing complex heterocyclic molecules in drug discovery and development pipelines.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable organotrifluoroborate reagent for palladium-catalyzed carbon-carbon bond formation under mild conditions.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides containing the 1,3,4-thiadiazole moiety.
• Materials Chemistry: Employed in the creation of organic electronic materials, ligands for catalysis, and advanced polymers.
• Process Chemistry & Scale-Up: Valued for its handling stability compared to some boronic acids, making it suitable for optimized manufacturing processes.
• Academic & Industrial R&D: A versatile tool for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Item	Details
Product Name	Potassium Trifluoro(5-Methyl-1,3,4-Thiadiazol-2-Yl)Borate
CAS No.	1245906-72-2
Molecular Formula	C3H3BF3KN2S
Molecular Weight	197.04 g/mol
Synonyms	Potassium (5-Methyl-1,3,4-thiadiazol-2-yl)trifluoroborate; 5-Methyl-1,3,4-thiadiazole-2-trifluoroborate Potassium Salt; (5-Methyl-1,3,4-thiadiazol-2-yl)trifluoroboronic Acid Potassium Salt; Potassium 5-Methyl-1,3,4-thiadiazol-2-yltrifluoroborate; 2-Trifluoroborato-5-methyl-1,3,4-thiadiazole Potassium Salt; Potassium Trifluoro(5-methyl-1,3,4-thiadiazol-2-yl)borate(1-); K-5-Methyl-1,3,4-thiadiazole-2-trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro(5-Methyl-1,3,4-Thiadiazol-2-Yl)Borate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) when opening to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
11B NMR Purity	≥ 97%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.