Description

Potassium (2-Chloropyrimidin-5-Yl)Trifluoroborate is a high-purity organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing pyrimidine-containing active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that incorporate the chloropyrimidine moiety.
• Material Science Research: Serves as a precursor for creating functional organic materials, including ligands for catalysis and components for organic electronics.
• Suzuki-Miyaura Cross-Coupling: The primary application, where it acts as a stable, air- and moisture-tolerant organoboron reagent for forming carbon-carbon bonds with aryl/heteroaryl halides.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry programs.
• Process Chemistry & Scale-Up: Suitable for optimization and scaling in the production of target molecules from gram to multi-kilogram quantities.

Basic Information

Product Name	Potassium (2-Chloropyrimidin-5-Yl)Trifluoroborate
CAS No.	1245906-70-0
Molecular Formula	C4H2BClF3KN2
Molecular Weight	220.43 g/mol
Synonyms	Potassium (2-Chloropyrimidin-5-yl)trifluoroborate; (2-Chloro-5-pyrimidinyl)trifluoroborate Potassium Salt; 2-Chloropyrimidine-5-trifluoroboronic Acid Potassium Salt; 5-(2-Chloropyrimidinyl)trifluoroborate Potassium; Potassium 2-Chloropyrimidin-5-yltrifluoroborate; 2-Chloro-5-pyrimidyltrifluoroborate Potassium; Potassium (2-Chloro-5-pyrimidinyl)trifluoroboranuide
EINECS	Contact for details

Quality Control

Our Potassium (2-Chloropyrimidin-5-Yl)Trifluoroborate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete batch-specific data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97%
19F NMR Purity	≥ 95%
11B NMR Purity	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.