Description

Potassium (5-Cyanopyridin-3-yl)trifluoroborate is a versatile and highly valuable organoboron reagent, specifically a potassium trifluoroborate salt. This compound is prized for its enhanced stability and handling properties compared to traditional boronic acids, making it a critical building block in modern synthetic chemistry. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures through robust cross-coupling reactions.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent in Suzuki-Miyaura cross-coupling reactions for the construction of biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Research & Development: Used to synthesize novel herbicide and fungicide candidates by introducing the functionalized pyridine moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Applications: Employed in the synthesis of organic electronic materials, such as those for OLEDs and conductive polymers, where the cyanopyridine unit modulates electronic properties.
• Chemical Biology & Probe Synthesis: Useful for labeling and modifying biomolecules or creating molecular probes for diagnostic and research purposes.
• Scale-up and Process Chemistry: Its stability makes it suitable for kilogram-scale manufacturing processes in fine chemical production.

Basic Information

Product Name	Potassium (5-Cyanopyridin-3-yl)trifluoroborate
CAS No.	1245906-68-6
Molecular Formula	C6H3BF3KN2
Molecular Weight	193.01 g/mol
Synonyms	Potassium (5-Cyanopyridin-3-yl)trifluoroboranuide; 3-Cyano-5-pyridyltrifluoroborate Potassium Salt; 5-Cyanopyridin-3-yltrifluoroborate Potassium Salt; Potassium 3-Cyano-5-pyridyltrifluoroborate; Potassium Trifluoro(5-cyanopyridin-3-yl)borate; (5-Cyano-3-pyridinyl)trifluoroborate Potassium Salt; 3-Pyridinecarbonitrile, 5-(trifluoroborato)-, potassium salt (1:1)
EINECS	Contact for details

Quality Control

Our Potassium (5-Cyanopyridin-3-yl)trifluoroborate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
11B NMR Purity	≥ 95%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.