Description

Potassium (4-Chloropyridin-3-yl)trifluoroborate is a versatile and highly valuable organoboron reagent, specifically a potassium organotrifluoroborate salt. This compound is a critical building block in modern synthetic chemistry, prized for its stability, ease of handling, and reactivity in key carbon-carbon bond-forming reactions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for complex molecule synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed coupling with aryl/heteroaryl halides to synthesize biaryl and heterobiaryl structures, a cornerstone of medicinal chemistry.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Serves as a precursor for creating novel herbicides, fungicides, and insecticides with complex heterocyclic architectures.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: A building block for creating organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology Probes: Useful for the synthesis of tagged molecules and probes for studying biological systems.

Basic Information

Product Name	Potassium (4-Chloropyridin-3-yl)trifluoroborate
CAS No.	1245906-67-5
Molecular Formula	C5H3BClF3KN
Molecular Weight	213.44 g/mol
Synonyms	Potassium (4-Chloro-3-pyridyl)trifluoroborate; 4-Chloro-3-pyridyltrifluoroboronic acid potassium salt; (4-Chloropyridin-3-yl)trifluoroboronic acid potassium salt; Potassium 4-Chloropyridine-3-trifluoroborate; 3-Pyridylboronic acid, 4-chloro-, potassium trifluoroborate; Potassium Trifluoro(4-chloro-3-pyridinyl)borate; K-4-Chloro-3-pyridyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium (4-Chloropyridin-3-yl)trifluoroborate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high chemical purity and consistent performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97%
1H NMR Purity	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in water, methanol, DMF; slightly soluble in THF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.