Description

Potassium (5-Amino-2-Chloropyridin-3-Yl)Trifluoroborate is a high-purity organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its stability and reactivity, serving as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients. Its specific functionalization enables the precise construction of complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing functionalized pyridine motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific chlorinated aminopyridine structures.
• Material Science Research: Employed in the development of novel organic electronic materials, ligands, and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: Specifically designed as a stable boronic acid surrogate for robust and efficient Suzuki-Miyaura cross-coupling under mild conditions.
• Chemical Biology Probes: Serves as a building block for creating labeled compounds and molecular probes used in diagnostic and biochemical research.

Basic Information

Product Name	Potassium (5-Amino-2-Chloropyridin-3-Yl)Trifluoroborate
CAS No.	1245906-63-1
Molecular Formula	C5H4BClF3KN2
Molecular Weight	237.45 g/mol
Synonyms	Potassium (5-Amino-2-chloropyridin-3-yl)trifluoroborate; (5-Amino-2-Chloro-3-pyridinyl)trifluoroborate Potassium Salt; 5-Amino-2-chloro-3-pyridyltrifluoroboronate Potassium; 2-Chloro-5-amino-3-pyridyltrifluoroborate Potassium Salt; Potassium 5-Amino-2-chloropyridine-3-trifluoroborate; 3-Pyridineboronic acid, 5-amino-2-chloro-, trifluoroborate(1-) potassium salt (1:1); K-5-Amino-2-Chloro-3-Pyridyltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium (5-Amino-2-Chloropyridin-3-Yl)Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent decomposition. Keep the container sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
19F NMR Purity	≥95%
11B NMR Purity	≥95%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.