Description

Potassium (5-Chloropyrimidin-2-Yl)Trifluoroborate is a high-purity organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. This compound is valued for its role in facilitating key cross-coupling reactions, particularly Suzuki-Miyaura couplings, due to its enhanced stability and handling properties compared to traditional boronic acids. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent in the Suzuki-Miyaura cross-coupling for constructing biaryl and heteroaryl motifs found in drug candidates.
• Agrochemical Research & Development: Used to create novel pyrimidine-based compounds for crop protection and pesticide development.
• Material Science: Serves as a precursor for synthesizing organic electronic materials, ligands, and functional polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of labeled compounds and molecular probes for biological studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring precise, scalable coupling reactions.

Basic Information

Product Name	Potassium (5-Chloropyrimidin-2-Yl)Trifluoroborate
CAS No.	1245906-58-4
Molecular Formula	C4H2BClF3KN2
Molecular Weight	220.43 g/mol
Synonyms	Potassium (5-Chloro-2-pyrimidinyl)trifluoroborate; 5-Chloro-2-pyrimidinyltrifluoroborate Potassium Salt; (5-Chloropyrimidin-2-yl)trifluoroboronic Acid Potassium Salt; Potassium 5-Chloropyrimidine-2-trifluoroborate; 2-(5-Chloropyrimidinyl) Potassium Trifluoroborate; Potassium Trifluoro(5-chloropyrimidin-2-yl)borate
EINECS	Contact for details

Quality Control

Our Potassium (5-Chloropyrimidin-2-Yl)Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure high chemical purity and consistent performance in sensitive coupling reactions. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR / 19F NMR	Conforms to structure
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.