Description

2-Hydroxymethyl-5-(Tributylstannyl)Thiazole is a specialized organotin-thiazole hybrid compound, serving as a critical building block in advanced synthetic chemistry. Its unique structure, combining a thiazole heterocycle with a tributylstannyl moiety, makes it a versatile reagent for cross-coupling reactions and material science applications. This high-value intermediate is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides, herbicides, and fungicides with enhanced efficacy.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers, conductive materials, and liquid crystals.
• Cross-Coupling Reactions: Serves as a crucial organotin reagent in Stille coupling reactions for the formation of carbon-carbon bonds under mild conditions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target identification.
• Catalyst Ligand Development: Investigated as a potential ligand precursor for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Hydroxymethyl-5-(Tributylstannyl)Thiazole
CAS No.	1245816-28-7
Molecular Formula	C16H31NOSSn
Molecular Weight	404.21 g/mol
Synonyms	5-(Tributylstannyl)-2-thiazolemethanol; 2-(Hydroxymethyl)-5-(tributylstannyl)thiazole; Thiazole, 2-(hydroxymethyl)-5-(tributylstannyl)-; Tributyl(2-(hydroxymethyl)thiazol-5-yl)stannane; 2-Thiazolemethanol, 5-(tributylstannyl)-; Stannane, tributyl[2-(hydroxymethyl)-5-thiazolyl]-; Organotin-thiazole intermediate
EINECS	Contact for details

Quality Control

Our 2-Hydroxymethyl-5-(Tributylstannyl)Thiazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including NMR, HPLC, and elemental analysis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation and light, the container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Tin (Sn) Content	Contact for details
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.