Description

8-Tributylstannyl[1,2,4]triazolo[1,5-a]pyridine is a specialized organotin compound featuring a triazolopyridine heterocyclic system. This advanced chemical intermediate is valued for its role in facilitating key cross-coupling reactions, such as the Stille reaction, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the creation of novel pesticides, herbicides, and fungicides that require the triazolopyridine moiety for biological activity.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for catalysis, and other functional organic compounds.
• Stille Cross-Coupling Reactions: Serves as a pivotal organotin reagent for the efficient transfer of the triazolopyridine group to various electrophilic partners under mild conditions.
• Chemical Biology Probes: Useful in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Item	Details
Product Name	8-Tributylstannyl[1,2,4]triazolo[1,5-a]pyridine
CAS No.	1245816-23-2
Molecular Formula	C₂₂H₃₈N₃Sn
Molecular Weight	487.26 g/mol
Synonyms	8-(Tributylstannyl)-[1,2,4]triazolo[1,5-a]pyridine; Tributyl(8-[1,2,4]triazolo[1,5-a]pyridin-8-yl)stannane; 8-Tributylstannyltriazolopyridine; 8-(Tri-n-butylstannyl)-1,2,4-triazolo[1,5-a]pyridine; 8-Stannyltriazolopyridine; Stannane, tributyl[8-[1,2,4]triazolo[1,5-a]pyridin-8-yl]-; 1245816-23-2
EINECS	Contact for details

Quality Control

Our production of 8-Tributylstannyl[1,2,4]triazolo[1,5-a]pyridine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR (1H, 13C, 119Sn) and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The compound is easily oxidized; prolonged exposure to air should be avoided. Keep the container in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Tin (Sn) Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.