Description

(S)-Tetrahydro-2H-Pyran-3-Amine Hydrochloride CAS NO 1245724-46-2 is a high-purity chiral amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides for enhanced efficacy and environmental safety.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic asymmetric synthesis.
• Peptidomimetics & Molecular Probes: Integral for constructing conformationally constrained peptide analogs and biochemical tools for drug discovery.
• Academic & Industrial R&D: A versatile building block for methodological development in organic chemistry and material science.

Basic Information

Product Name	(S)-Tetrahydro-2H-Pyran-3-Amine Hydrochloride
CAS No.	1245724-46-2
Molecular Formula	C5H12ClNO
Molecular Weight	137.61 g/mol
Synonyms	(S)-3-Aminotetrahydropyran Hydrochloride; (3S)-3-Aminotetrahydro-2H-pyran Hydrochloride; (S)-Tetrahydro-2H-pyran-3-amine HCl; (S)-3-Aminotetrahydropyran HCl; (S)-THP-3-amine Hydrochloride; (S)-Aminotetrahydropyran Hydrochloride; (S)-3-Pyranamine, tetrahydro-, hydrochloride
EINECS	Contact for details

Quality Control

Our (S)-Tetrahydro-2H-Pyran-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination and standard purity assays, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and residual solvent content is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (ee, HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.