Description

2-Amino-2-(3-Chloro-2-Fluorophenyl)Ethan-1-Ol is a high-purity, functionalized amino alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both amino and hydroxyl groups on a chiral center adjacent to a halogenated aromatic ring, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where its halogenated aromatic core contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring specific aromatic-amino alcohol motifs.
• Academic and Contract Research: A valuable compound for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	2-Amino-2-(3-Chloro-2-Fluorophenyl)Ethan-1-Ol
CAS No.	1245697-83-9
Molecular Formula	C8H9ClFNO
Molecular Weight	189.61 g/mol
Synonyms	2-Amino-2-(3-chloro-2-fluorophenyl)ethanol; 1-(3-Chloro-2-fluorophenyl)-2-aminoethanol; (R/S)-2-Amino-2-(3-chloro-2-fluorophenyl)ethan-1-ol; 3-Chloro-2-fluoro-β-aminoethylbenzene; α-Amino-(3-chloro-2-fluorophenyl)methanol; 2-(3-Chloro-2-fluorophenyl)-2-aminoethanol; Amino alcohol intermediate 1245697-83-9
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-2-(3-Chloro-2-Fluorophenyl)Ethan-1-Ol is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.