Description

{2-[(3-Methoxyphenyl)Dimethylsilyl]Phenyl}Methanol is a specialized organosilicon intermediate featuring a unique silyl-protected benzyl alcohol moiety. This compound matters for its role as a versatile building block in advanced organic synthesis, particularly in the development of novel materials and active pharmaceutical ingredients (APIs). Industries such as pharmaceutical R&D, agrochemical manufacturing, and specialty polymer production require this high-purity intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Ligand Precursor: Used in the preparation of sophisticated ligands for catalysis and asymmetric synthesis.
• Material Science Building Block: Integral component in the development of advanced silicone-based polymers and hybrid organic-inorganic materials.
• Agrochemical Research: Serves as a critical intermediate for creating new-generation pesticides and herbicides with enhanced efficacy.
• Surface Modification Agent: Employed to functionalize surfaces or nanoparticles due to its reactive silane and alcohol groups.
• Cross-coupling Reactions: Acts as a substrate or protecting group in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck).

Basic Information

Product Name	{2-[(3-Methoxyphenyl)Dimethylsilyl]Phenyl}Methanol
CAS No.	1244855-82-0
Molecular Formula	C₁₆H₂₀O₂Si
Molecular Weight	272.42 g/mol
Synonyms	[2-[(3-Methoxyphenyl)dimethylsilyl]phenyl]methanol; (2-{[Dimethyl(3-methoxyphenyl)silyl]}phenyl)methanol; 2-[(3-Methoxyphenyl)dimethylsilyl]benzyl alcohol; Dimethyl(3-methoxyphenyl)[2-(hydroxymethyl)phenyl]silane; CAS 1244855-82-0; Organosilicon alcohol intermediate; Silylated benzyl alcohol derivative
EINECS	Contact for details

Quality Control

Our {2-[(3-Methoxyphenyl)Dimethylsilyl]Phenyl}Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.