Description

3-Cyclopropoxy-5-(Trifluoromethyl)Aniline is a high-value aromatic amine derivative featuring a cyclopropoxy ether and a trifluoromethyl group, making it a versatile and reactive building block in advanced organic synthesis. Its unique structure provides excellent potential for modulating the physicochemical properties of target molecules, particularly in enhancing lipophilicity and metabolic stability. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially in kinase inhibitor and central nervous system (CNS) active molecule research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group is a critical pharmacophore.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Fluorine Chemistry Building Block: Essential for introducing fluorine-containing motifs into complex molecular architectures in medicinal and synthetic chemistry.

Basic Information

Product Name	3-Cyclopropoxy-5-(Trifluoromethyl)Aniline
CAS No.	1243471-01-3
Molecular Formula	C10H10F3NO
Molecular Weight	217.19 g/mol
Synonyms	3-(Cyclopropoxy)-5-(trifluoromethyl)aniline; 3-Cyclopropoxy-5-(trifluoromethyl)benzenamine; 5-(Trifluoromethyl)-3-cyclopropoxyaniline; 1-Amino-3-cyclopropoxy-5-(trifluoromethyl)benzene; 3-Cyclopropoxy-α,α,α-trifluoro-m-toluidine; m-Cyclopropoxy-α,α,α-trifluoroaniline
EINECS	Contact for details

Quality Control

Our production of 3-Cyclopropoxy-5-(Trifluoromethyl)Aniline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.