Description

6-(tert-Butyl)-8-Fluorophthalazin-1(2H)-One is a high-purity fluorinated phthalazinone derivative, a key advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which is crucial for constructing complex molecules with specific biological or material properties. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its fluorinated heterocyclic structure.
• Material Science: Serves as a precursor for specialty polymers and organic electronic materials due to its rigid, fused-ring system.
• Chemical Synthesis: Employed as a versatile synthon in academic and industrial research for constructing complex heterocyclic compounds.
• Ligand & Catalyst Development: Its structure makes it a candidate for developing novel ligands in catalytic processes and metal-organic frameworks (MOFs).

Basic Information

Item	Information
Product Name	6-(tert-Butyl)-8-Fluorophthalazin-1(2H)-One
CAS No.	1242156-59-7
Molecular Formula	C₁₂H₁₃FN₂O
Molecular Weight	220.25 g/mol
Synonyms	8-Fluoro-6-(tert-butyl)phthalazin-1(2H)-one; 6-tert-Butyl-8-fluorophthalazin-1(2H)-one; 8-Fluoro-6-(1,1-dimethylethyl)-1(2H)-phthalazinone; 1242156-59-7; 6-(tert-Butyl)-8-fluorophthalazin-1-ol (tautomer); 6-(tert-Butyl)-8-fluoro-1,2-dihydrophthalazine-1-one
EINECS	Contact for details

Quality Control

Our 6-(tert-Butyl)-8-Fluorophthalazin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your R&D and scale-up activities with reliable and traceable quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.