Description

4-Bromooxazole is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the oxazole moiety with a reactive halogen handle for further functionalization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a building block for creating advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport layers.
• Ligand and Catalyst Development: Employed in the preparation of specialized nitrogen-containing ligands for transition metal catalysis.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological processes and target engagement.
• Cross-Coupling Reactions: Acts as a competent substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl and other conjugated systems.

Basic Information

Product Name	4-Bromooxazole
CAS No.	1240598-57-5
Molecular Formula	C3H2BrNO
Molecular Weight	147.96 g/mol
Synonyms	4-Bromo-1,3-oxazole; Oxazole, 4-bromo-; 4-Bromooxazole; 1,3-Oxazole, 4-bromo-; Bromooxazole; 4-Br-oxazole
EINECS	Contact for details

Quality Control

Our 4-Bromooxazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting critical parameters such as assay and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.