Description

4-Bromo-1-Methyl-2,3-Dihydro-1H-1,3-Benzodiazol-2-One is a specialized heterocyclic organic compound that serves as a valuable brominated building block in advanced chemical synthesis. Its molecular structure makes it a critical intermediate for the development of novel pharmaceuticals and agrochemicals, where precise functionalization is required. This high-purity intermediate is essential for research and development chemists and process scale-up teams in the life sciences and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require a halogenated benzimidazolone core.
• Organic Synthesis Reagent: Serves as a versatile electrophile or coupling partner in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for introducing complex substituents.
• Material Science Precursor: Potential monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Biology Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme inhibition and receptor binding.

Basic Information

Product Name	4-Bromo-1-Methyl-2,3-Dihydro-1H-1,3-Benzodiazol-2-One
CAS No.	1240593-33-2
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	4-Bromo-1-methyl-1,3-dihydro-2H-benzimidazol-2-one; 1-Methyl-4-bromo-2,3-dihydro-1H-benzimidazol-2-one; 4-Bromo-1-methyl-2-benzimidazolinone; 2H-Benzimidazol-2-one, 4-bromo-1,3-dihydro-1-methyl-; 1240593-33-2; 4-Bromo-1-methylbenzimidazolin-2-one
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Methyl-2,3-Dihydro-1H-1,3-Benzodiazol-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and internal quality standards. Our commitment to cGMP principles ensures reliability for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.