Description

3-Carboxy-4-Methyl-Morpholine Hcl is a high-purity, functionalized morpholine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile chiral building block and key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of complex, high-value molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used as a precursor in the development of new-generation herbicides and fungicides with improved efficacy.
• Ligand and Catalyst Development: Serves as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific chirality and functionalization.

Basic Information

Product Name	3-Carboxy-4-Methyl-Morpholine Hcl
CAS No.	1240518-90-4
Molecular Formula	C7H13NO3 • HCl
Molecular Weight	195.64 g/mol (Free base: 159.18 g/mol)
Synonyms	4-Methylmorpholine-3-carboxylic acid hydrochloride; 3-Carboxy-4-methylmorpholine hydrochloride; Morpholine-3-carboxylic acid, 4-methyl-, hydrochloride; (4-Methylmorpholin-3-yl)carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Carboxy-4-Methyl-Morpholine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.