Description

(3R,4R)-3-(((R)-1-Phenylethyl)Amino)Tetrahydro-2H-Pyran-4-Ol CAS NO 1240390-30-0 is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its precise three-dimensional structure makes it a critical building block for constructing complex molecules with specific biological activity. This compound is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of new active pharmaceutical ingredients (APIs), particularly in areas requiring high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential CNS drugs and enzyme inhibitors.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block to induce stereoselectivity in complex organic transformations.
• Catalyst Ligand Precursor: Used in the synthesis of sophisticated ligands for asymmetric catalysis in fine chemical production.
• Academic & Industrial Research: Serves as a valuable reference standard and starting material in medicinal chemistry and process chemistry research programs.
• Custom Synthesis: A foundational component for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects for clients.

Basic Information

Product Name	(3R,4R)-3-(((R)-1-Phenylethyl)Amino)Tetrahydro-2H-Pyran-4-Ol
CAS No.	1240390-30-0
Molecular Formula	C14H21NO2
Molecular Weight	235.33 g/mol
Synonyms	(3R,4R)-3-[(1R)-1-Phenylethylamino]tetrahydro-2H-pyran-4-ol; (3R,4R)-3-[(R)-1-Phenylethylamino]tetrahydropyran-4-ol; (3R,4R)-3-((R)-1-Phenylethylamino)tetrahydro-2H-pyran-4-ol; Tetrahydro-2H-pyran-4-ol, 3-[(1R)-1-phenylethylamino]-, (3R,4R)-; Chiral Pyranol Amine Intermediate; (R,R,R)-Pyranol Amine Derivative
EINECS	Contact for details

Quality Control

Our (3R,4R)-3-(((R)-1-Phenylethyl)Amino)Tetrahydro-2H-Pyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) determination and purity assessment, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.