Description

Methyl 3-(2-(2-(2-(Tosyloxy)Ethoxy)Ethoxy)Ethoxy)Propanoate is a specialized organic compound featuring a polyethylene glycol (PEG) spacer terminated with a methyl ester and a tosylate group. This unique bifunctional structure makes it a valuable chemical building block for the synthesis of complex molecules and functional materials. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications requiring precise molecular conjugation and controlled functionalization.

Application

• Pharmaceutical Intermediates: Acts as a key precursor in the synthesis of prodrugs, targeted drug delivery systems, and linker molecules for antibody-drug conjugates (ADCs).
• Bioconjugation Chemistry: Used for PEGylation of peptides, proteins, and other biomolecules to enhance solubility, stability, and circulation time.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for creating hydrophilic polymers, hydrogels, and surface coatings with tailored properties.
• Chemical Probes & Diagnostics: Employed in the development of fluorescent probes, biosensors, and diagnostic reagents where a reactive tosylate group is required for labeling.
• Organic Synthesis: A versatile reagent for introducing PEG chains and ester functionalities into target molecules under mild conditions.

Basic Information

Product Name	Methyl 3-(2-(2-(2-(Tosyloxy)Ethoxy)Ethoxy)Ethoxy)Propanoate
CAS No.	1239588-09-0
Molecular Formula	C17H28O9S
Molecular Weight	408.46 g/mol
Synonyms	Methyl 3,6,9-trioxa-12-azatetradecan-14-oate 12-tosylate; Methyl PEG3 tosylate; Methyl-PEG3-OTs; Methyl 3-[2-[2-[2-(4-methylbenzenesulfonyloxy)ethoxy]ethoxy]ethoxy]propanoate; Tetraethylene glycol monomethyl ether tosylate ester; PEG3 methyl ester tosylate; Tos-PEG3-methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(2-(2-(2-(Tosyloxy)Ethoxy)Ethoxy)Ethoxy)Propanoate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.