Description

Potassium 5-Bromopyridine-3-Trifluoroborate is a high-purity organotrifluoroborate salt, a versatile and stable building block for advanced organic synthesis. Its value lies in its enhanced stability and handling properties compared to traditional boronic acids, enabling more efficient cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific brominated pyridine motifs.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and conductive polymers.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for biochemical and diagnostic applications.
• Scale-up and Process Chemistry: Its improved stability makes it suitable for optimization and scaling up of coupling reactions in pilot and manufacturing settings.

Basic Information

Item	Details
Product Name	Potassium 5-Bromopyridine-3-Trifluoroborate
CAS No.	1239437-45-6
Molecular Formula	C5H3BBrF3KN
Molecular Weight	269.90 g/mol
Synonyms	5-Bromo-3-pyridyltrifluoroborate potassium salt; Potassium (5-Bromopyridin-3-yl)trifluoroborate; 3-Bromo-5-pyridyltrifluoroboronate potassium; 5-Bromopyridine-3-boronic acid, trifluoroborate potassium salt; (5-Bromopyridin-3-yl)trifluoroboronic acid potassium salt; Potassium 5-Bromo-3-pyridyltrifluoroborate; 3-Pyridylboronic acid, 5-bromo-, trifluoroborate potassium derivative
EINECS	Contact for details

Quality Control

Every batch of Potassium 5-Bromopyridine-3-Trifluoroborate is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure high purity and consistency for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to maintain stability and purity. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
NMR Purity (19F)	≥ 95.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.