Description

Boc-Aminooxy-Peg3-Amine CAS NO 1235514-18-7 is a heterobifunctional polyethylene glycol (PEG) linker featuring a Boc-protected aminooxy group and a primary amine terminus. This compound is essential for creating stable, site-specific bioconjugates and for introducing hydrophilic PEG spacers into complex molecules. It is a critical reagent for researchers and manufacturers in pharmaceutical development, bioconjugation, and advanced materials science, enabling the synthesis of antibody-drug conjugates (ADCs), peptide modifications, and functionalized surfaces.

Application

• Bioconjugation and ADC Development: Site-specific conjugation of drugs, dyes, or other payloads to antibodies, proteins, or peptides via oxime ligation.
• PEGylation Chemistry: Introducing hydrophilic PEG spacers to improve the solubility, stability, and pharmacokinetic properties of therapeutic molecules.
• Crosslinking and Surface Functionalization: Creating functionalized surfaces for biosensors, microarrays, and biomaterials using the amine group for further coupling.
• Solid-Phase Peptide Synthesis (SPPS): Incorporation of aminooxy functionality into peptide chains for post-synthetic modification.
• Small Molecule Prodrug Synthesis: Designing cleavable linkers for targeted drug delivery systems.
• Polymer Chemistry: Serving as a monomer or building block for synthesizing functionalized polymers and hydrogels.

Basic Information

Product Name	Boc-Aminooxy-Peg3-Amine
CAS No.	1235514-18-7
Molecular Formula	C16H33N3O6
Molecular Weight	363.45 g/mol
Synonyms	1-Amino-11-((tert-butoxycarbonyl)amino)-3,6,9-trioxaundecane; Boc-NH-O-PEG3-NH2; tert-Butyl (1-amino-3,6,9-trioxaundecan-11-yl)carbamate; Amino-PEG3-aminooxy, Boc-protected; Boc-Aminooxy-PEG3-amine; 3,6,9-Trioxaundecane-1,11-diamine, 11-[[(1,1-dimethylethoxy)carbonyl]amino]-; Heterobifunctional PEG linker Boc-OA-PEG3-NH2; Boc-protected aminooxy-PEG3-amine
EINECS	Contact for details

Quality Control

Our Boc-Aminooxy-Peg3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.