Description

Ethyl 4-Chloro-1H-Pyrrolo[2,3-C]Pyridine-2-Carboxylate is a high-purity heterocyclic building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs. It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of targeted therapies.

Application

• Pharmaceutical Intermediate: Key synthon for the construction of complex drug candidates, especially kinase inhibitors targeting various cancers and inflammatory diseases.
• Organic Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its versatile pyrrolopyridine core.
• Biochemical Research: Employed in the development of chemical probes and tool compounds for biological pathway analysis and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.
• Agrochemical Research: Potential intermediate in the discovery of new agrochemicals, leveraging its heterocyclic structure for novel modes of action.
• Material Science Precursor: Investigated as a precursor for advanced organic electronic materials due to its fused ring system.

Basic Information

Product Name	Ethyl 4-Chloro-1H-Pyrrolo[2,3-C]Pyridine-2-Carboxylate
CAS No.	1234616-15-9
Molecular Formula	C10H9ClN2O2
Molecular Weight	224.64 g/mol
Synonyms	Ethyl 4-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate; 4-Chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid ethyl ester; 1H-Pyrrolo[2,3-c]pyridine-2-carboxylic acid, 4-chloro-, ethyl ester; 1234616-15-9; 4-Chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate ethyl ester; Ethyl 4-chloro-7-azaindole-2-carboxylate; 4-Chloro-7-azaindole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-1H-Pyrrolo[2,3-C]Pyridine-2-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch and supplied upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.