Description

1-(4-Nitrophenyl)-3-(Piperidin-4-Yl)Ureahydrochloride is a high-purity, synthetically derived chemical building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of novel therapeutic agents, particularly those targeting central nervous system and metabolic disorders. It is primarily utilized by R&D chemists, process development scientists, and manufacturers in the pharmaceutical and biotechnology sectors seeking reliable, high-quality raw materials for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent, selective enzyme inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and commercial manufacturing of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A versatile scaffold for contract research organizations (CROs) and CDMOs producing bespoke molecules for client projects.

Basic Information

Product Name	1-(4-Nitrophenyl)-3-(Piperidin-4-Yl)Ureahydrochloride
CAS No.	1233955-44-6
Molecular Formula	C12H17ClN4O3
Molecular Weight	300.74 g/mol
Synonyms	1-(4-Nitrophenyl)-3-(4-piperidinyl)urea hydrochloride; 4-[[(4-Nitrophenyl)amino]carbonyl]piperidine hydrochloride; 1-(4-Nitrophenyl)-3-piperidin-4-yl-urea hydrochloride; Urea, N-(4-nitrophenyl)-N'-(4-piperidinyl)-, hydrochloride; 4-[(4-Nitroanilino)carbonyl]piperidine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Nitrophenyl)-3-(Piperidin-4-Yl)Ureahydrochloride is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.