Description

4-(3-Fluoro-2-Nitrophenoxy)Tetrahydro-2H-Pyran is a high-purity, advanced pharmaceutical intermediate characterized by its unique fluorinated nitrophenoxy pyran structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its fluorinated aromatic moiety for enhanced biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing heterocyclic compounds and introducing specific functional groups in complex organic molecules.
• Material Science Research: Investigated for the development of specialty polymers and advanced materials with tailored optical or electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	4-(3-Fluoro-2-Nitrophenoxy)Tetrahydro-2H-Pyran
CAS No.	1233953-06-4
Molecular Formula	C11H12FNO4
Molecular Weight	241.22 g/mol
Synonyms	4-(3-Fluoro-2-nitrophenoxy)oxane; Tetrahydro-2H-pyran-4-yl 3-fluoro-2-nitrophenyl ether; 3-Fluoro-2-nitrophenyl tetrahydro-2H-pyran-4-yl ether; 4-(3-Fluoro-2-nitrophenoxy)tetrahydropyran; 2H-Pyran, tetrahydro-4-(3-fluoro-2-nitrophenoxy)-; 4-(3-Fluoro-2-nitro-phenoxy)-tetrahydro-pyran
EINECS	Contact for details

Quality Control

Our 4-(3-Fluoro-2-Nitrophenoxy)Tetrahydro-2H-Pyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.