Description

4-[(2-Fluoro-4-Nitrophenoxy)Methyl]Tetrahydro-2H-Pyran is a specialized fluorinated nitrophenoxy derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both a fluorinated aromatic ring and a tetrahydro-2H-pyran moiety, makes it a critical building block for constructing complex molecules with targeted properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in developing new generation herbicides, fungicides, and insecticides where the nitrophenoxy group is a common active pharmacophore.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for creating advanced functional materials used in display technologies and organic electronics.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments, leveraging the nitro and fluoro substituents for color and stability modification.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl ether systems.
• Chemical Biology Probes: Useful in designing molecular probes and tags for studying biological systems due to its reactive handles for further functionalization.

Basic Information

Product Name	4-[(2-Fluoro-4-Nitrophenoxy)Methyl]Tetrahydro-2H-Pyran
CAS No.	1233953-00-8
Molecular Formula	C12H14FNO4
Molecular Weight	255.24 g/mol
Synonyms	4-[(2-Fluoro-4-nitrophenoxy)methyl]oxane; Tetrahydro-2H-pyran-4-ylmethyl 2-fluoro-4-nitro phenyl ether; 2-Fluoro-4-nitrophenyl tetrahydro-2H-pyran-4-ylmethyl ether; 4-(2-Fluoro-4-nitro-phenoxymethyl)-tetrahydro-pyran; (Tetrahydro-2H-pyran-4-yl)methyl 2-fluoro-4-nitrophenyl ether; 2-Fluoro-4-nitro-1-((tetrahydro-2H-pyran-4-yl)methoxy)benzene
EINECS	Contact for details

Quality Control

Our production of 4-[(2-Fluoro-4-Nitrophenoxy)Methyl]Tetrahydro-2H-Pyran adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your regulatory and process development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.