Description

3-Iodo-Imidazo[1,2-B]Pyridazine is a high-value halogenated heterocyclic building block of significant interest in modern organic synthesis. Its core structure makes it a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds with targeted biological or electronic properties.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic scaffold.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed as a molecular probe or a tagging reagent in bioconjugation and proteomics research.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form new carbon-carbon bonds.
• Library Synthesis: Used in parallel and combinatorial chemistry for generating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	3-Iodo-Imidazo[1,2-B]Pyridazine
CAS No.	1233690-88-4
Molecular Formula	C6H4IN3
Molecular Weight	245.02 g/mol
Synonyms	3-Iodoimidazo[1,2-b]pyridazine; Imidazo[1,2-b]pyridazine, 3-iodo-; 3-Iodo-1H-imidazo[1,2-b]pyridazine; 1233690-88-4; AI3-36425; ZINC000103249476; AKOS040759625; BDBM50389381; SCHEMBL21829027; CTK8G7116
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-Imidazo[1,2-B]Pyridazine is produced and tested under strict quality management protocols to ensure consistency and reliability for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC), identity confirmation (by 1H NMR and IR), and levels of specific impurities. Our quality systems are designed to support cGMP and ISO standards for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.