Description

n-[(1S,2S)-2-[Bis(Phenylmethyl)Amino]Cyclohexyl]-N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea is a sophisticated chiral thiourea derivative, a class of compounds renowned for their utility as organocatalysts and selective ligands. This compound matters for its potential to enable highly enantioselective transformations in complex organic synthesis, offering a pathway to high-value, optically pure intermediates. It is primarily needed by research and development chemists in the pharmaceutical and fine chemical industries for applications in asymmetric catalysis and as a building block for advanced molecular scaffolds.

Application

• As an organocatalyst for enantioselective reactions, such as Michael additions and acylations.
• As a chiral ligand or auxiliary in transition metal catalysis for asymmetric synthesis.
• In pharmaceutical research for the development of active pharmaceutical ingredients (APIs) with specific stereochemistry.
• As a key synthetic intermediate in the preparation of more complex, biologically active molecules.
• For methodology development in academic and industrial organic chemistry laboratories.
• In the fine chemicals sector for producing specialty chemicals with high enantiomeric purity.

Basic Information

Product Name	n-[(1S,2S)-2-[Bis(Phenylmethyl)Amino]Cyclohexyl]-N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea
CAS No.	1233369-39-5
Molecular Formula	C29H29F6N3S
Molecular Weight	557.62 g/mol
Synonyms	(1S,2S)-N,N-Dibenzyl-2-({[3,5-bis(trifluoromethyl)phenyl]carbamothioyl}amino)cyclohexanamine; (1S,2S)-N,N-Dibenzyl-2-[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]cyclohexanamine; Chiral Thiourea Catalyst; (S,S)-Dibenzylcyclohexanediamine-Based Thiourea; N-[(1S,2S)-2-(Dibenzylamino)cyclohexyl]-N'-[3,5-bis(trifluoromethyl)phenyl]thiourea; Asymmetric Thiourea Organocatalyst; 1233369-39-5; CAS 1233369-39-5
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as assay, enantiomeric excess, and impurity profiles. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.