Description

cis-3-Amino-Tetrahydropyran-4-Carboxylic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a rigid tetrahydropyran scaffold. This compound is a critical chiral building block for the synthesis of complex molecules, offering significant value in medicinal chemistry and drug discovery. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs) and peptidomimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of protease inhibitors, enzyme modulators, and other small-molecule therapeutics.
• Peptidomimetic Design: Used to introduce conformational constraint and metabolic stability into peptide backbones for enhanced drug-like properties.
• Chemical Biology Research: Serves as a specialized building block in the synthesis of chemical probes and tool compounds for target validation.
• Agrochemical Synthesis: Potential intermediate in the creation of advanced, chiral active ingredients for crop protection.
• Ligand Development: Employed in the synthesis of complex ligands for catalysis and material science applications.

Basic Information

Product Name	cis-3-Amino-Tetrahydropyran-4-Carboxylic Acid
CAS No.	1233010-36-0
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	(3R,4S)-3-Aminooxane-4-carboxylic acid; (3R,4S)-3-Aminotetrahydropyran-4-carboxylic acid; cis-3-Amino-4-carboxytetrahydropyran; 3-Amino-THP-4-carboxylic acid; 3-Aminooxane-4-carboxylic acid; 4-Carboxy-3-aminotetrahydropyran; 1233010-36-0; cis-3-Amino-THP-4-COOH
EINECS	Contact for details

Quality Control

Our cis-3-Amino-Tetrahydropyran-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.