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n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-2-[3-(2-Fluorophenyl)-6-Oxopyridazin-1(6H)-Yl]-n-Methylacetamide CAS NO 1232810-48-8


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CAS No.:1232810-48-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-2-[3-(2-Fluorophenyl)-6-Oxopyridazin-1(6H)-Yl]-n-Methylacetamide is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is valued for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic chemistry. It is essential for research institutions and pharmaceutical manufacturers engaged in the synthesis of next-generation drug candidates.

Application

  • Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
  • Active Pharmaceutical Ingredient (API) Development: Used in research and development for constructing the core scaffold of potential APIs with pyridazinone and fluorophenyl moieties.
  • Medicinal Chemistry Research: A valuable tool compound for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.
  • Biochemical Research: May be utilized in the development of enzyme inhibitors or receptor modulators for biochemical assays.

Basic Information

Item Details
Product Name n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-2-[3-(2-Fluorophenyl)-6-Oxopyridazin-1(6H)-Yl]-n-Methylacetamide
CAS No. 1232810-48-8
Molecular Formula C17H18FN3O4S
Molecular Weight 379.41 g/mol
Synonyms 2-[3-(2-Fluorophenyl)-6-oxopyridazin-1(6H)-yl]-N-methyl-N-(1,1-dioxidotetrahydro-3-thienyl)acetamide; 2-(3-(2-Fluorophenyl)-6-oxo-1,6-dihydropyridazin-1-yl)-N-methyl-N-(1,1-dioxido-1,2-thiolan-3-yl)acetamide; N-(1,1-Dioxidotetrahydro-3-thienyl)-2-[3-(2-fluorophenyl)-6-oxo-1(6H)-pyridazinyl]-N-methylacetamide; 1232810-48-8; Fluorophenyl Pyridazinone Acetamide Derivative
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Quality Control

Our n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-2-[3-(2-Fluorophenyl)-6-Oxopyridazin-1(6H)-Yl]-n-Methylacetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere if specified.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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