Description

6-(2-Chlorophenyl)-2-[2-(1,2-Dimethyl-1H-Indol-3-Yl)-2-Oxoethyl]Pyridazin-3(2H)-One is a high-purity, advanced pharmaceutical intermediate critical for modern drug discovery and development. This compound serves as a key building block in the synthesis of novel therapeutic agents, offering researchers a reliable and consistent starting material. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new chemical entities, particularly in the areas of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) with potential biological activity.
• Drug Discovery Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization, particularly for targets involving indole and pyridazine scaffolds.
• Chemical Biology Probe Synthesis: Serves as a core structure for developing molecular probes to study biological pathways and protein functions.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling of related drug substances.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.

Basic Information

Product Name	6-(2-Chlorophenyl)-2-[2-(1,2-Dimethyl-1H-Indol-3-Yl)-2-Oxoethyl]Pyridazin-3(2H)-One
CAS No.	1232769-63-9
Molecular Formula	C22H18ClN3O2
Molecular Weight	391.85 g/mol
Synonyms	6-(2-Chlorophenyl)-2-[2-(1,2-dimethyl-1H-indol-3-yl)-2-oxoethyl]-2,3-dihydropyridazin-3-one; 2-[2-(1,2-Dimethyl-1H-indol-3-yl)-2-oxoethyl]-6-(2-chlorophenyl)pyridazin-3(2H)-one; 6-(2-Chlorophenyl)-2-[2-(1,2-dimethylindol-3-yl)-2-oxoethyl]pyridazin-3(2H)-one; CAS 1232769-63-9; Pyridazinone derivative, indole-substituted; 1,2-Dimethyl-3-[2-oxo-2-[6-(2-chlorophenyl)-3-oxopyridazin-1-yl]ethyl]indole
EINECS	Contact for details

Quality Control

Our 6-(2-Chlorophenyl)-2-[2-(1,2-Dimethyl-1H-Indol-3-Yl)-2-Oxoethyl]Pyridazin-3(2H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material suitable for research and non-GMP development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.