Description

trans-4-Amino-3-(Methoxy)Tetrahydropyran is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its unique stereochemistry and functional groups, which make it a versatile precursor for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioisosteres: The tetrahydropyran scaffold is valuable for designing peptide mimics and bioisosteric replacements in medicinal chemistry.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and for exploring new synthetic routes.

Basic Information

Product Name	trans-4-Amino-3-(Methoxy)Tetrahydropyran
CAS No.	1232060-77-3
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	(3R,4S)-4-Amino-3-methoxytetrahydro-2H-pyran; (3S,4R)-4-Amino-3-methoxytetrahydro-2H-pyran; 3-Methoxy-4-aminotetrahydropyran; 4-Amino-3-methoxytetrahydro-2H-pyran; trans-4-Amino-3-methoxytetrahydropyran; 2H-Pyran, tetrahydro-4-amino-3-methoxy-, trans-; Tetrahydropyran, 4-amino-3-methoxy-, trans-
EINECS	Contact for details

Quality Control

Our trans-4-Amino-3-(Methoxy)Tetrahydropyran is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.