Description

(4-Chloro-2-Fluorophenyl)(6-Chloro-2-Methylimidazo[1,2-B]Pyridazin-3-Yl)Methanon is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists working on novel small molecule therapeutics, particularly in kinase inhibitor programs. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in the synthesis of targeted drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Preclinical Development: Serves as a critical raw material for producing compounds for biological screening and toxicology studies.
• Contract Manufacturing: Supplied to CDMOs for scale-up synthesis under cGMP conditions for clinical trial material production.
• Academic Research: Utilized in university and institutional labs for chemical biology and drug discovery projects.
• Chemical Reference Standard: Can be supplied as a high-purity standard for analytical method development and validation.

Basic Information

Product Name	(4-Chloro-2-Fluorophenyl)(6-Chloro-2-Methylimidazo[1,2-B]Pyridazin-3-Yl)Methanon
CAS No.	1229236-80-9
Molecular Formula	C₁₄H₈Cl₂FN₃O
Molecular Weight	324.14 g/mol
Synonyms	(4-Chloro-2-fluorophenyl)(6-chloro-2-methylimidazo[1,2-b]pyridazin-3-yl)methanone; 1-(4-Chloro-2-fluorophenyl)-2-(6-chloro-2-methylimidazo[1,2-b]pyridazin-3-yl)ethanone (tautomer); 1229236-80-9; Methanone, (4-chloro-2-fluorophenyl)(6-chloro-2-methylimidazo[1,2-b]pyridazin-3-yl)-; Imidazo[1,2-b]pyridazine methanone derivative; 6-Chloro-2-methyl-3-(4-chloro-2-fluorobenzoyl)imidazo[1,2-b]pyridazine
EINECS	Contact for details

Quality Control

Our (4-Chloro-2-Fluorophenyl)(6-Chloro-2-Methylimidazo[1,2-B]Pyridazin-3-Yl)Methanon is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support development with custom purity grades, from research (95%+) to cGMP standards for advanced clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; therefore, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.