Description

1-(2-Bromophenyl)Cyclobutan-1-Amine is a specialized organic building block featuring a cyclobutane ring fused with a brominated aromatic amine, offering unique steric and electronic properties for advanced molecular construction. This compound is valued for its role as a key chiral intermediate in the synthesis of complex pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical development companies engaged in creating new therapeutic agents, particularly in areas requiring constrained three-dimensional scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Serves as a building block for developing new generation herbicides and pesticides with enhanced selectivity.
• Material Science: Used in the research and development of advanced organic electronic materials and liquid crystals.
• Academic & R&D: Employed in organic chemistry research for methodology development and the study of strained ring systems.
• Chemical Biology: Utilized as a probe or linker in the design of molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	1-(2-Bromophenyl)Cyclobutan-1-Amine
CAS No.	1228994-69-1
Molecular Formula	C10H12BrN
Molecular Weight	226.11 g/mol
Synonyms	1-(2-Bromophenyl)cyclobutanamine; 2-Bromo-α-cyclobutylbenzenemethanamine; 1-Amino-1-(2-bromophenyl)cyclobutane; Cyclobutanamine, 1-(2-bromophenyl)-; 1-(2-Bromophenyl)cyclobutan-1-amine; (2-Bromophenyl)(cyclobutyl)methanamine; 2-Bromo-α-cyclobutylbenzylamine
EINECS	Contact for details

Quality Control

Our 1-(2-Bromophenyl)Cyclobutan-1-Amine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced intermediates, ensuring suitability for demanding research and pre-clinical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.