Description

4,4-Difluorocycloheptanone is a high-purity fluorinated ketone building block of significant interest in advanced organic synthesis. This compound matters for its unique structural motif, which combines a seven-membered ring with strategically placed fluorine atoms, enabling precise modulation of electronic and steric properties in target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as medicinal chemistry, ligand design, and the development of novel fluorinated materials.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of novel bioactive molecules, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Research: Used in the synthesis of advanced fluorinated pesticides and herbicides, where fluorine substitution can enhance bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized fluorinated ligands for transition metal catalysis and organocatalysis.
• Materials Science: Employed in the research and development of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing fluorinated analogs of natural products or biochemical probes for mechanism-of-action studies.
• Academic & Industrial R&D: A versatile building block for methodological development in organic synthesis and fluorine chemistry.

Basic Information

Product Name	4,4-Difluorocycloheptanone
CAS No.	1227807-93-3
Molecular Formula	C7H10F2O
Molecular Weight	148.15 g/mol
Synonyms	4,4-Difluorocycloheptanone; 4,4-Difluoro-cycloheptanone; Cycloheptanone, 4,4-difluoro-; 4,4-Difluoroheptanone; 4,4-Difluorocycloheptan-1-one; 4,4-Difluorocycloheptan-1-one; 4,4-Difluorocycloheptanone (CAS 1227807-93-3)
EINECS	Contact for details

Quality Control

Our 4,4-Difluorocycloheptanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.