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[2-(6-Chloropyridazin-3-Ylamino)-Ethyl]-Carbamic Acid tert-Butyl Ester CAS NO 1227266-42-3


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CAS No.:1227266-42-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[2-(6-Chloropyridazin-3-Ylamino)-Ethyl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting the development of new drugs.

Application

  • Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
  • Medicinal Chemistry Research: Serves as a crucial building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
  • API Synthesis: Used in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), where its specific functional groups enable strategic molecular transformations.
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the scale-up and production of clinical trial materials and commercial APIs.
  • Biochemical Research: Employed in the development of chemical probes and tool compounds for investigating biological pathways and target validation.

Basic Information

Product Name [2-(6-Chloropyridazin-3-Ylamino)-Ethyl]-Carbamic Acid tert-Butyl Ester
CAS No. 1227266-42-3
Molecular Formula C11H17ClN4O2
Molecular Weight 272.73 g/mol
Synonyms tert-Butyl N-[2-[(6-chloropyridazin-3-yl)amino]ethyl]carbamate; 2-[(6-Chloro-3-pyridazinyl)amino]ethylcarbamic Acid 1,1-Dimethylethyl Ester; BOC-6-Chloro-3-aminopyridazine Ethylamine; N-Boc-2-((6-chloropyridazin-3-yl)amino)ethanamine; (2-((6-Chloropyridazin-3-yl)amino)ethyl)carbamic acid tert-butyl ester; 1227266-42-3; 6-Chloro-3-((2-((tert-butoxycarbonyl)amino)ethyl)amino)pyridazine
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Quality Control

Our [2-(6-Chloropyridazin-3-Ylamino)-Ethyl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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