Description

2-[4-(2-Methoxyphenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid is a specialized organic acid building block of significant interest in advanced synthetic chemistry. This compound matters for its role as a key intermediate in the development of complex pharmaceutical molecules and fine chemicals. It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functional additive in the development of advanced polymers and specialty coatings.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Catalyst Ligand Precursor: Acts as a starting material for synthesizing complex chiral ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-[4-(2-Methoxyphenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid
CAS No.	1226173-72-3
Molecular Formula	C14H18O4
Molecular Weight	250.29 g/mol
Synonyms	2-[4-(2-Methoxyphenyl)oxan-4-yl]acetic acid; 2-(4-(2-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)acetic acid; 4-(2-Methoxyphenyl)-4-(carboxymethyl)tetrahydropyran; 2-(4-(2-Methoxyphenyl)tetrahydropyran-4-yl)acetic acid; 1226173-72-3; 2-(4-(2-Methoxyphenyl)-3,4,5,6-tetrahydro-2H-pyran-4-yl)acetic acid; 2-(4-(2-Methoxyphenyl)tetrahydro-2H-pyran-4-yl)ethanoic acid
EINECS	Contact for details

Quality Control

Our 2-[4-(2-Methoxyphenyl)-Tetrahydro-2H-Pyran-4-Yl]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases, oxidizing agents, and incompatible materials. Handle and store in accordance with good industrial hygiene and safety practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.